Trade-offs in Engineering Sugar Utilization Pathways for Titratable Control
نویسندگان
چکیده
منابع مشابه
Trade-offs in Engineering Sugar Utilization Pathways for Titratable Control
Titratable systems are common tools in metabolic engineering to tune the levels of enzymes and cellular components as part of pathway optimization. For nonmodel microorganisms with limited genetic tools, inducible sugar utilization pathways offer built-in titratable systems. However, these pathways can exhibit undesirable single-cell behaviors that hamper the uniform and tunable control of gene...
متن کاملEvolving Engineering Design Trade-offs
In the engineering design process, it is important to know the engineering trade-offs achievable under various design preferences and strategies. In this paper, a family of engineering design trade-offs are evolved from an automatic design synthesis methodology based on evolutionary computation. The complete Pareto optima frontier can be evolved by a consideration of fitness function that aggre...
متن کاملDesign Choices/Engineering Trade-Offs
T his special issue addresses the business of producing computing machines and the choices computer architects and implementors must make to succeed in the marketplace. This focus represents the sober reflection that computer architecture is not yet a science, even though parts of the discipline can be considered science and most of it often involves scientific methodology. To a large extent, t...
متن کاملAggregation functions for engineering design trade-offs
The choice of an aggregation function is a common problem in Multi Attribute Decision Making (MADM) systems. The Method of Imprecision (MoI) is a formal theory for the manipulation of preliminary design information that represents preferences among design alternatives with the mathematics of fuzzy sets. The MoI formulates the preliminary design problem as a MADM problem. To date, two aggregatio...
متن کاملDefining Pathways and Trade-offs Toward Universal Health Coverage; Comment on “Ethical Perspective: Five Unacceptable Trade-offs on the Path to Universal Health Coverage”
The World Health Organization’s (WHO’s) World Health Report 2010, “Health systems financing, the path to universal coverage,” promoted universal health coverage (UHC) as an aspirational objective for country health systems. Yet, in addition to the dimensions of services and coverage, distribution of coverage in the population, and financial risk protection highlighted by the report, the conside...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: ACS Synthetic Biology
سال: 2014
ISSN: 2161-5063,2161-5063
DOI: 10.1021/sb400162z